منابع مشابه
Inhalation Studies: Foundations and Techniques
Inhalation Studies: Foundations and Techniques is a book which attempts to draw together the salient points of inhalation hardware and pulmonary toxicology. Although the book suffers from the omission of some important basic information, in general it provides a good background to the fundamentals of inhalation toxicology. The material is well framed and presented as an introductory treatment. ...
متن کاملDifferential dose responses of pulmonary tumor types in the rat after inhalation of plutonium dioxide aerosols.
Dose responses were compared among primary lung tumors and their histological types induced by a single inhalation exposure of female Wistar strain rats to submicron-size and polydispersed aerosols of plutonium dioxide (239PuO2). While the primary lung tumors were found only in 2.3% of the unexposed control animals, the frequency of all the primary lung tumors in the exposed animals was 44% at ...
متن کاملComparisons of pulmonary carcinogenesis in rats following inhalation exposure to plutonium dioxide or X-ray irradiation.
Radiation-induced pulmonary carcinogenesis was compared in female Wistar rats following either inhalation exposure to alpha-emitting (239)PuO(2) aerosols, whole-body or thoracic X-ray irradiation. Dose-dependent survival reduction was correlated with increased malignant lung tumors at doses over 0.45 Gy, reaching the maximum incidence of 90% at 6.6-8.5 Gy in (239)Pu-exposed rats. While the diff...
متن کاملDosimetry considerations for animal aerosol inhalation studies.
The determination of the dose of inhaled aerosol particles in animal subjects is not a trivial exercise. In its simplest form, the dose is the amount (particle number, mass or other relevant metric) that deposits in the respiratory tract. The amount deposited will depend on the aerosol particle sizes (e.g. the aerodynamic diameter size distribution), the duration of exposure, the exposure syste...
متن کاملInhalation studies with drugs of abuse.
In recent years, smoking or inhalation of drugs has become a popular route of administration among drug users. Various drugs of different classes have been abused by inhalation or smoking, including phencyclidine (PCP), cocaine, heroin, methamphetamine, and marijuana. This increased popu-larity of smoking drugs has resulted from the fast onset of drug action and fears related to contracting acq...
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ژورنال
عنوان ژورنال: Archives of Environmental Health: An International Journal
سال: 1961
ISSN: 0003-9896
DOI: 10.1080/00039896.1961.10662921